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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 22 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • DIP2
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP56
  • box C/D snoRNP complex
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • PWP2
  • cytoplasm
  • nuclear outer membrane
  • 90S preribosome
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • cytokinesis
  • ribosome biogenesis
  • snoRNA binding
  • RRP9
  • nuclear outer membrane
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP21
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 8.0545E-33 22 72 18 6292
    nuclear outer membrane 7.7265E-22 22 86 14 6292
    nuclear membrane 4.6986E-21 22 97 14 6292
    outer membrane 3.3138E-17 22 178 14 6292
    organelle outer membrane 3.3138E-17 22 178 14 6292
    ribonucleoprotein complex 1.0664E-16 22 514 18 6292
    nuclear envelope 1.6288E-16 22 199 14 6292
    nucleolus 3.7439E-16 22 211 14 6292
    nuclear membrane-endoplasmic reticulum network 1.4345E-15 22 232 14 6292
    endomembrane system 2.6416E-12 22 398 14 6292
    nuclear lumen 1.5523E-11 22 453 14 6292
    envelope 6.7928E-11 22 505 14 6292
    organelle envelope 6.7928E-11 22 505 14 6292
    nuclear part 7.794E-11 22 1103 18 6292
    organelle lumen 2.4606E-9 22 660 14 6292
    intracellular organelle lumen 2.4606E-9 22 660 14 6292
    membrane part 2.5614E-9 22 662 14 6292
    organelle membrane 4.6073E-9 22 692 14 6292
    membrane-enclosed lumen 5.363E-9 22 700 14 6292
    macromolecular complex 6.5084E-8 22 1635 18 6292
    non-membrane-bounded organelle 3.2163E-7 22 959 14 6292
    intracellular non-membrane-bounded organelle 3.2163E-7 22 959 14 6292
    nucleus 2.5653E-6 22 2041 18 6292
    preribosome 4.8539E-6 22 34 4 6292
    membrane 5.2833E-6 22 1198 14 6292
    intracellular organelle part 1.5565E-5 22 2282 18 6292
    organelle part 1.5565E-5 22 2282 18 6292
    small-subunit processome 1.736E-4 22 6 2 6292
    nucleolar part 4.7878E-4 22 45 3 6292
    90S preribosome 1.5377E-3 22 17 2 6292
    intracellular part 4.7906E-3 22 4938 22 6292
    intracellular 5.6476E-3 22 4975 22 6292
    box C/D snoRNP complex 6.9813E-3 22 2 1 6292
    Noc4p-Nop14p complex 6.9813E-3 22 2 1 6292
    membrane-bounded organelle 7.357E-3 22 3771 19 6292
    intracellular membrane-bounded organelle 7.357E-3 22 3771 19 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 1.0142E-28 22 346 22 6292
    ribonucleoprotein complex biogenesis 5.9191E-28 22 374 22 6292
    rRNA processing 1.4251E-25 22 128 17 6292
    rRNA metabolic process 4.8486E-25 22 137 17 6292
    maturation of SSU-rRNA 2.3386E-24 22 59 14 6292
    cellular component biogenesis 6.4039E-22 22 694 22 6292
    ncRNA processing 1.4264E-21 22 215 17 6292
    ncRNA metabolic process 3.1957E-20 22 257 17 6292
    RNA processing 2.6736E-17 22 380 17 6292
    RNA metabolic process 1.2904E-10 22 954 17 6292
    rRNA modification 2.6704E-9 22 18 5 6292
    gene expression 1.5335E-8 22 1283 17 6292
    nucleic acid metabolic process 7.2322E-8 22 1415 17 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.5382E-7 22 1566 17 6292
    cellular nitrogen compound metabolic process 2.3388E-6 22 1770 17 6292
    nitrogen compound metabolic process 2.8001E-6 22 1791 17 6292
    RNA modification 3.3536E-6 22 70 5 6292
    cellular macromolecule metabolic process 1.0529E-4 22 2285 17 6292
    macromolecule metabolic process 1.5681E-4 22 2349 17 6292
    cellular process 4.2871E-4 22 4426 22 6292
    primary metabolic process 2.8529E-3 22 2896 17 6292
    ribosomal small subunit biogenesis 3.6053E-3 22 26 2 6292
    cellular metabolic process 5.2302E-3 22 3033 17 6292
    metabolic process 8.7346E-3 22 3157 17 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 1.1157E-23 22 31 12 6292
    RNA binding 4.9463E-10 22 367 12 6292
    nucleic acid binding 4.2686E-7 22 666 12 6292
    binding 8.5102E-5 22 1294 13 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle