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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 20 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BMS1
  • nucleus
  • cytoplasm
  • mitochondrion
  • nuclear outer membrane
  • nucleolus
  • ribosome assembly
  • rRNA processing
  • GTP binding
  • ECM16
  • mitochondrion
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • RNA helicase activity
  • EMG1
  • nucleus
  • cytoplasm
  • nuclear microtubule
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • ENP1
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • preribosome, small subunit precursor
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • ENP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • molecular_function
  • IMP3
  • small-subunit processome
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • KRE33
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • MPP10
  • nucleus
  • small-subunit processome
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • molecular_function
  • NAN1
  • RENT complex
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • NOC4
  • nucleus
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • NOP1
  • nuclear outer membrane
  • nucleolus
  • ribosome
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • RNA methylation
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • snoRNA 3'-end processing
  • methyltransferase activity
  • NOP14
  • mitochondrion
  • Noc4p-Nop14p complex
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosomal small subunit biogenesis
  • ribosome biogenesis
  • snoRNA binding
  • SOF1
  • nuclear outer membrane
  • nucleolus
  • small nuclear ribonucleoprotein complex
  • small nucleolar ribonucleoprotein complex
  • rRNA modification
  • maturation of SSU-rRNA
  • snoRNA binding
  • UTP10
  • mitochondrion
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP20
  • cytoplasm
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • rRNA processing
  • snoRNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • UTP30
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • ribosome biogenesis
  • molecular_function
  • UTP4
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP6
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • ribosome biogenesis
  • snoRNA binding
  • UTP7
  • nuclear outer membrane
  • small nucleolar ribonucleoprotein complex
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    small nucleolar ribonucleoprotein complex 2.3798E-26 20 72 15 6292
    nuclear outer membrane 1.6275E-20 20 86 13 6292
    nuclear membrane 8.6158E-20 20 97 13 6292
    nucleolus 6.2278E-19 20 211 15 6292
    outer membrane 3.1331E-16 20 178 13 6292
    organelle outer membrane 3.1331E-16 20 178 13 6292
    nuclear envelope 1.3707E-15 20 199 13 6292
    nuclear membrane-endoplasmic reticulum network 1.0306E-14 20 232 13 6292
    ribonucleoprotein complex 1.125E-14 20 514 16 6292
    nuclear lumen 6.4374E-14 20 453 15 6292
    endomembrane system 1.1089E-11 20 398 13 6292
    organelle lumen 1.658E-11 20 660 15 6292
    intracellular organelle lumen 1.658E-11 20 660 15 6292
    membrane-enclosed lumen 3.9131E-11 20 700 15 6292
    nuclear part 8.4032E-11 20 1103 17 6292
    envelope 2.2711E-10 20 505 13 6292
    organelle envelope 2.2711E-10 20 505 13 6292
    non-membrane-bounded organelle 3.6788E-9 20 959 15 6292
    intracellular non-membrane-bounded organelle 3.6788E-9 20 959 15 6292
    membrane part 6.6659E-9 20 662 13 6292
    organelle membrane 1.1519E-8 20 692 13 6292
    preribosome 4.9628E-8 20 34 5 6292
    preribosome, small subunit precursor 5.4611E-7 20 6 3 6292
    macromolecular complex 6.5307E-7 20 1635 16 6292
    nucleus 1.7888E-6 20 2041 17 6292
    membrane 8.2853E-6 20 1198 13 6292
    Noc4p-Nop14p complex 9.6001E-6 20 2 2 6292
    intracellular organelle part 1.0237E-5 20 2282 17 6292
    organelle part 1.0237E-5 20 2282 17 6292
    Noc complex 9.5453E-5 20 5 2 6292
    small-subunit processome 1.4291E-4 20 6 2 6292
    nucleolar part 3.5799E-4 20 45 3 6292
    90S preribosome 1.2688E-3 20 17 2 6292
    membrane-bounded organelle 3.5096E-3 20 3771 18 6292
    intracellular membrane-bounded organelle 3.5096E-3 20 3771 18 6292
    intracellular part 7.7919E-3 20 4938 20 6292
    intracellular 9.0491E-3 20 4975 20 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 3.7651E-26 20 346 20 6292
    ribonucleoprotein complex biogenesis 1.863E-25 20 374 20 6292
    rRNA processing 1.4936E-24 20 128 16 6292
    rRNA metabolic process 4.7104E-24 20 137 16 6292
    ncRNA processing 8.5291E-21 20 215 16 6292
    maturation of SSU-rRNA 1.6773E-20 20 59 12 6292
    cellular component biogenesis 5.5528E-20 20 694 20 6292
    ncRNA metabolic process 1.5884E-19 20 257 16 6292
    RNA processing 8.9732E-17 20 380 16 6292
    RNA metabolic process 1.852E-10 20 954 16 6292
    gene expression 1.7304E-8 20 1283 16 6292
    nucleic acid metabolic process 7.5787E-8 20 1415 16 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 3.4468E-7 20 1566 16 6292
    cellular nitrogen compound metabolic process 2.0981E-6 20 1770 16 6292
    nitrogen compound metabolic process 2.4931E-6 20 1791 16 6292
    rRNA modification 2.1745E-5 20 18 3 6292
    ribosomal small subunit biogenesis 6.8171E-5 20 26 3 6292
    cellular macromolecule metabolic process 8.1666E-5 20 2285 16 6292
    macromolecule metabolic process 1.2005E-4 20 2349 16 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.3325E-4 20 13 2 6292
    cellular process 8.6878E-4 20 4426 20 6292
    RNA modification 1.3127E-3 20 70 3 6292
    primary metabolic process 2.0259E-3 20 2896 16 6292
    cellular metabolic process 3.678E-3 20 3033 16 6292
    metabolic process 6.1059E-3 20 3157 16 6292
    ncRNA 5'-end processing 9.5071E-3 20 3 1 6292
    endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5071E-3 20 3 1 6292
    endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 9.5071E-3 20 3 1 6292
    rRNA 5'-end processing 9.5071E-3 20 3 1 6292
    RNA 5'-end processing 9.5071E-3 20 3 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    snoRNA binding 9.1158E-22 20 31 11 6292
    RNA binding 2.3967E-9 20 367 11 6292
    nucleic acid binding 1.1825E-6 20 666 11 6292
    binding 1.3142E-4 20 1294 12 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle