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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
KEM1
  • cytoplasm
  • cytoplasmic mRNA processing body
  • nuclear outer membrane
  • filamentous growth
  • response to exogenous dsRNA
  • telomere maintenance
  • traversing start control point of mitotic cell cycle
  • karyogamy involved in conjugation with cellular fusion
  • mRNA catabolic process
  • 5'-3' exoribonuclease activity
  • deoxyribonuclease activity
  • recombinase activity
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20B
  • ribosome biogenesis
  • translation
  • structural constituent of ribosome
  • RPS11A, RPS11B
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS13
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS4B, RPS4A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • ribosome
  • 90S preribosome
  • intracellular
  • regulation of translation
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • STM1
  • cytoplasm
  • nuclear telomere cap complex
  • anti-apoptosis
  • telomere maintenance
  • DNA binding
  • telomeric DNA binding
  • UTP22
  • nucleus
  • nuclear outer membrane
  • nucleolus
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • ribosome biogenesis
  • rRNA processing
  • snoRNA binding
  • YGR054W
  • ribosome
  • translational initiation
  • translation initiation factor activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    90S preribosome 7.585E-9 10 17 4 6292
    ribonucleoprotein complex 7.3162E-8 10 514 8 6292
    preribosome 1.4589E-7 10 34 4 6292
    cytosolic ribosome 2.282E-7 10 101 5 6292
    cytosolic small ribosomal subunit 2.3149E-7 10 38 4 6292
    cytosolic part 5.8882E-7 10 122 5 6292
    ribosome 1.6359E-6 10 290 6 6292
    small ribosomal subunit 3.323E-6 10 73 4 6292
    ribosomal subunit 4.4125E-6 10 183 5 6292
    non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    intracellular non-membrane-bounded organelle 9.5787E-6 10 959 8 6292
    cytosol 3.7818E-5 10 284 5 6292
    macromolecular complex 4.0767E-5 10 1635 9 6292
    intracellular organelle part 6.1675E-3 10 2282 8 6292
    organelle part 6.1675E-3 10 2282 8 6292
    nuclear outer membrane 7.7386E-3 10 86 2 6292
    nuclear membrane 9.7663E-3 10 97 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 2.6446E-7 10 376 7 6292
    maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 8.2018E-7 10 13 3 6292
    cellular macromolecule metabolic process 3.9402E-5 10 2285 10 6292
    macromolecule metabolic process 5.1966E-5 10 2349 10 6292
    regulation of translation 8.0877E-5 10 57 3 6292
    gene expression 8.885E-5 10 1283 8 6292
    maturation of SSU-rRNA 8.9707E-5 10 59 3 6292
    posttranscriptional regulation of gene expression 9.9146E-5 10 61 3 6292
    regulation of cellular protein metabolic process 1.3725E-4 10 68 3 6292
    regulation of protein metabolic process 1.7664E-4 10 74 3 6292
    cellular protein metabolic process 3.0812E-4 10 1074 7 6292
    primary metabolic process 4.2311E-4 10 2896 10 6292
    protein metabolic process 4.4321E-4 10 1136 7 6292
    cellular macromolecule biosynthetic process 5.882E-4 10 1187 7 6292
    macromolecule biosynthetic process 5.946E-4 10 1189 7 6292
    cellular metabolic process 6.7219E-4 10 3033 10 6292
    rRNA processing 8.8893E-4 10 128 3 6292
    metabolic process 1.0041E-3 10 3157 10 6292
    rRNA metabolic process 1.0834E-3 10 137 3 6292
    ribosome biogenesis 1.4482E-3 10 346 4 6292
    negative regulation of programmed cell death 1.5893E-3 10 1 1 6292
    negative regulation of cell death 1.5893E-3 10 1 1 6292
    anti-apoptosis 1.5893E-3 10 1 1 6292
    negative regulation of apoptosis 1.5893E-3 10 1 1 6292
    ribonucleoprotein complex biogenesis 1.9363E-3 10 374 4 6292
    cellular biosynthetic process 3.3987E-3 10 1567 7 6292
    biosynthetic process 3.8954E-3 10 1602 7 6292
    ncRNA processing 3.9518E-3 10 215 3 6292
    regulation of cellular process 4.6602E-3 10 796 5 6292
    regulation of biological process 5.4298E-3 10 824 5 6292
    regulation of programmed cell death 6.3436E-3 10 4 1 6292
    regulation of cell death 6.3436E-3 10 4 1 6292
    regulation of apoptosis 6.3436E-3 10 4 1 6292
    ncRNA metabolic process 6.5282E-3 10 257 3 6292
    traversing start control point of mitotic cell cycle 9.5019E-3 10 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 2.5591E-7 10 212 6 6292
    structural molecule activity 4.0905E-6 10 339 6 6292
    nucleic acid binding 1.9872E-4 10 666 6 6292
    rRNA binding 2.6962E-4 10 16 2 6292
    RNA binding 1.8047E-3 10 367 4 6292
    5'-3' exoribonuclease activity 3.1764E-3 10 2 1 6292
    recombinase activity 6.3436E-3 10 4 1 6292
    binding 7.3119E-3 10 1294 6 6292
    5'-3' exonuclease activity 9.5019E-3 10 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle