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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 14 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
IMG1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • IMG2
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MHR1
  • nucleus
  • mitochondrion
  • mitochondrial genome maintenance
  • transcription regulator activity
  • MRP7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • peptidyltransferase activity
  • MRPL1
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • aerobic respiration
  • translation
  • structural constituent of ribosome
  • MRPL17
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL23
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • MRPL35
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL36
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL39
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL4
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL44
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • telomere maintenance
  • translation
  • structural constituent of ribosome
  • MRPL6
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • MRPL7
  • mitochondrion
  • mitochondrial large ribosomal subunit
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    organellar large ribosomal subunit 1.2859E-27 14 50 13 6292
    mitochondrial large ribosomal subunit 1.2859E-27 14 50 13 6292
    organellar ribosome 5.9198E-24 14 90 13 6292
    mitochondrial ribosome 5.9198E-24 14 90 13 6292
    large ribosomal subunit 9.5228E-23 14 110 13 6292
    mitochondrial matrix 5.6381E-20 14 176 13 6292
    mitochondrial lumen 5.6381E-20 14 176 13 6292
    ribosomal subunit 9.5191E-20 14 183 13 6292
    ribosome 4.3827E-17 14 290 13 6292
    mitochondrial part 2.8946E-14 14 475 13 6292
    ribonucleoprotein complex 8.1265E-14 14 514 13 6292
    organelle lumen 2.1184E-12 14 660 13 6292
    intracellular organelle lumen 2.1184E-12 14 660 13 6292
    membrane-enclosed lumen 4.5533E-12 14 700 13 6292
    mitochondrion 3.1923E-11 14 1125 14 6292
    non-membrane-bounded organelle 2.6914E-10 14 959 13 6292
    intracellular non-membrane-bounded organelle 2.6914E-10 14 959 13 6292
    macromolecular complex 2.5299E-7 14 1635 13 6292
    cytoplasmic part 2.1603E-6 14 2482 14 6292
    organelle part 1.7098E-5 14 2282 13 6292
    intracellular organelle part 1.7098E-5 14 2282 13 6292
    cytoplasm 3.3016E-4 14 3552 14 6292
    membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular membrane-bounded organelle 7.6409E-4 14 3771 14 6292
    intracellular organelle 2.2276E-3 14 4070 14 6292
    organelle 2.2353E-3 14 4071 14 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.3478E-15 14 376 13 6292
    cellular protein metabolic process 1.1602E-9 14 1074 13 6292
    protein metabolic process 2.3899E-9 14 1136 13 6292
    cellular macromolecule biosynthetic process 4.204E-9 14 1187 13 6292
    macromolecule biosynthetic process 4.296E-9 14 1189 13 6292
    gene expression 1.1412E-8 14 1283 13 6292
    cellular biosynthetic process 1.4726E-7 14 1567 13 6292
    biosynthetic process 1.9514E-7 14 1602 13 6292
    cellular macromolecule metabolic process 1.7382E-5 14 2285 13 6292
    macromolecule metabolic process 2.456E-5 14 2349 13 6292
    primary metabolic process 3.2929E-4 14 2896 13 6292
    cellular metabolic process 5.8003E-4 14 3033 13 6292
    metabolic process 9.4511E-4 14 3157 13 6292
    cellular process 7.2188E-3 14 4426 14 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 6.8176E-19 14 212 13 6292
    structural molecule activity 3.4453E-16 14 339 13 6292
    peptidyltransferase activity 6.6614E-3 14 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle