From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.473917179196] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nuclear telomeric heterochromatin | 2.224E-3 | 2 | 7 | 1 | 6292 |
telomeric heterochromatin | 2.224E-3 | 2 | 7 | 1 | 6292 |
nuclear heterochromatin | 2.224E-3 | 2 | 7 | 1 | 6292 |
heterochromatin | 2.224E-3 | 2 | 7 | 1 | 6292 |
telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
nuclear telomere cap complex | 3.4937E-3 | 2 | 11 | 1 | 6292 |
nuclear chromosome, telomeric region | 7.2981E-3 | 2 | 23 | 1 | 6292 |
chromosome, telomeric region | 8.5646E-3 | 2 | 27 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
telomere maintenance in response to DNA damage | 3.1786E-4 | 2 | 1 | 1 | 6292 |
protection from non-homologous end joining at telomere | 3.1786E-4 | 2 | 1 | 1 | 6292 |
telomere capping | 1.5888E-3 | 2 | 5 | 1 | 6292 |
transcription from RNA polymerase II promoter | 2.8267E-3 | 2 | 335 | 2 | 6292 |
telomere maintenance via telomere lengthening | 4.1283E-3 | 2 | 13 | 1 | 6292 |
telomere maintenance via telomerase | 4.1283E-3 | 2 | 13 | 1 | 6292 |
RNA-dependent DNA replication | 4.1283E-3 | 2 | 13 | 1 | 6292 |
transcription, DNA-dependent | 6.3792E-3 | 2 | 503 | 2 | 6292 |
RNA biosynthetic process | 6.5067E-3 | 2 | 508 | 2 | 6292 |
transcription | 7.6839E-3 | 2 | 552 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
transcription factor activity | 9.8679E-5 | 2 | 63 | 2 | 6292 |
DNA binding | 1.6492E-3 | 2 | 256 | 2 | 6292 |
transcription regulator activity | 2.8947E-3 | 2 | 339 | 2 | 6292 |