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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.474976911567]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
LAC1
  • endoplasmic reticulum
    		•
  • ceramide biosynthetic process
  • aging
    		•
  • sphingosine N-acyltransferase activity
    		•
    LIP1
  • nuclear envelope
  • endoplasmic reticulum membrane
  • endoplasmic reticulum
    		•
  • ceramide biosynthetic process
    		•
  • sphingosine N-acyltransferase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    endoplasmic reticulum 3.3381E-3 2 364 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ceramide biosynthetic process 1.5158E-7 2 3 2 6292
    sphingoid biosynthetic process 1.5158E-7 2 3 2 6292
    ceramide metabolic process 1.0611E-6 2 7 2 6292
    sphingoid metabolic process 1.819E-6 2 9 2 6292
    membrane lipid biosynthetic process 8.6401E-6 2 19 2 6292
    sphingolipid biosynthetic process 8.6401E-6 2 19 2 6292
    membrane lipid metabolic process 2.1979E-5 2 30 2 6292
    sphingolipid metabolic process 2.1979E-5 2 30 2 6292
    lipid biosynthetic process 4.2367E-4 2 130 2 6292
    cellular lipid metabolic process 8.5067E-4 2 184 2 6292
    lipid metabolic process 1.4491E-3 2 240 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    sphingosine N-acyltransferase activity 1.5158E-7 2 3 2 6292
    N-acyltransferase activity 3.552E-5 2 38 2 6292
    transferase activity, transferring acyl groups other than amino-acyl groups 2.1151E-4 2 92 2 6292
    acyltransferase activity 2.1151E-4 2 92 2 6292
    transferase activity, transferring acyl groups 2.8654E-4 2 107 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle