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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.645758174467]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

mitochondrial matrix 7.7811E-4 2 176 2 6292
mitochondrial lumen 7.7811E-4 2 176 2 6292
mitochondrial oxoglutarate dehydrogenase complex 9.5344E-4 2 3 1 6292
oxoglutarate dehydrogenase complex 9.5344E-4 2 3 1 6292
mitochondrial pyruvate dehydrogenase complex 1.9064E-3 2 6 1 6292
pyruvate dehydrogenase complex 1.9064E-3 2 6 1 6292
glycine cleavage complex 1.9064E-3 2 6 1 6292
mitochondrial part 5.6881E-3 2 475 2 6292
nucleoid 8.248E-3 2 26 1 6292
mitochondrial nucleoid 8.248E-3 2 26 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

acetyl-CoA metabolic process 9.6001E-6 2 20 2 6292
valine catabolic process 3.1786E-4 2 1 1 6292
valine metabolic process 3.1786E-4 2 1 1 6292
isoleucine catabolic process 3.1786E-4 2 1 1 6292
coenzyme metabolic process 3.6076E-4 2 120 2 6292
cofactor metabolic process 5.9526E-4 2 154 2 6292
acetyl-CoA biosynthetic process from pyruvate 6.3568E-4 2 2 1 6292
L-serine metabolic process 6.3568E-4 2 2 1 6292
L-serine biosynthetic process 6.3568E-4 2 2 1 6292
leucine catabolic process 6.3568E-4 2 2 1 6292
isoleucine metabolic process 9.5344E-4 2 3 1 6292
acetyl-CoA biosynthetic process 1.2712E-3 2 4 1 6292
branched chain family amino acid catabolic process 1.2712E-3 2 4 1 6292
malate metabolic process 1.2712E-3 2 4 1 6292
glycine catabolic process 1.9064E-3 2 6 1 6292
serine family amino acid catabolic process 2.5415E-3 2 8 1 6292
glycine metabolic process 2.5415E-3 2 8 1 6292
leucine metabolic process 2.5415E-3 2 8 1 6292
organic acid metabolic process 2.793E-3 2 333 2 6292
oxoacid metabolic process 2.793E-3 2 333 2 6292
carboxylic acid metabolic process 2.793E-3 2 333 2 6292
cellular ketone metabolic process 3.0157E-3 2 346 2 6292
serine family amino acid biosynthetic process 3.811E-3 2 12 1 6292
cellular catabolic process 4.3405E-3 2 415 2 6292
tricarboxylic acid cycle 4.7627E-3 2 15 1 6292
acetyl-CoA catabolic process 4.7627E-3 2 15 1 6292
branched chain family amino acid metabolic process 5.7138E-3 2 18 1 6292
catabolic process 6.2027E-3 2 496 2 6292
coenzyme catabolic process 6.3477E-3 2 20 1 6292
cofactor catabolic process 6.9813E-3 2 22 1 6292
serine family amino acid metabolic process 8.5646E-3 2 27 1 6292
dicarboxylic acid metabolic process 9.5139E-3 2 30 1 6292
cellular amino acid catabolic process 9.5139E-3 2 30 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

dihydrolipoyl dehydrogenase activity 3.1786E-4 2 1 1 6292
oxoglutarate dehydrogenase (succinyl-transferring) activity 6.3568E-4 2 2 1 6292
L-malate dehydrogenase activity 1.2712E-3 2 4 1 6292
pyruvate dehydrogenase (acetyl-transferring) activity 1.2712E-3 2 4 1 6292
pyruvate dehydrogenase activity 1.2712E-3 2 4 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 1.5888E-3 2 5 1 6292
malate dehydrogenase activity 1.5888E-3 2 5 1 6292
glycine dehydrogenase (decarboxylating) activity 1.9064E-3 2 6 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 1.9064E-3 2 6 1 6292
oxidoreductase activity 1.9877E-3 2 281 2 6292
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor 2.224E-3 2 7 1 6292
oxidoreductase activity, acting on the CH-NH2 group of donors 3.811E-3 2 12 1 6292
oxidoreductase activity, acting on sulfur group of donors 6.3477E-3 2 20 1 6292
oxidoreductase activity, acting on NADH or NADPH 6.6645E-3 2 21 1 6292
oxidoreductase activity, acting on the aldehyde or oxo group of donors 7.9314E-3 2 25 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle