From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.649856320831] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
PDI1 |
|
|
|
SCJ1 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
endoplasmic reticulum lumen | 1.4147E-6 | 2 | 8 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein folding | 1.5173E-4 | 2 | 78 | 2 | 6292 |
ER-nucleus signaling pathway | 3.1764E-3 | 2 | 10 | 1 | 6292 |
endoplasmic reticulum unfolded protein response | 3.1764E-3 | 2 | 10 | 1 | 6292 |
cellular response to biotic stimulus | 3.1764E-3 | 2 | 10 | 1 | 6292 |
cellular response to unfolded protein | 3.1764E-3 | 2 | 10 | 1 | 6292 |
cellular response to protein stimulus | 3.1764E-3 | 2 | 10 | 1 | 6292 |
response to endoplasmic reticulum stress | 3.1764E-3 | 2 | 10 | 1 | 6292 |
response to unfolded protein | 6.3477E-3 | 2 | 20 | 1 | 6292 |
response to biotic stimulus | 6.3477E-3 | 2 | 20 | 1 | 6292 |
cellular response to organic substance | 6.3477E-3 | 2 | 20 | 1 | 6292 |
response to protein stimulus | 6.3477E-3 | 2 | 20 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein disulfide oxidoreductase activity | 1.5888E-3 | 2 | 5 | 1 | 6292 |
protein disulfide isomerase activity | 1.5888E-3 | 2 | 5 | 1 | 6292 |
intramolecular oxidoreductase activity, interconverting keto- and enol-groups | 1.5888E-3 | 2 | 5 | 1 | 6292 |
intramolecular oxidoreductase activity, transposing S-S bonds | 1.5888E-3 | 2 | 5 | 1 | 6292 |
disulfide oxidoreductase activity | 1.9064E-3 | 2 | 6 | 1 | 6292 |
chaperone binding | 4.4455E-3 | 2 | 14 | 1 | 6292 |
intramolecular oxidoreductase activity | 6.0308E-3 | 2 | 19 | 1 | 6292 |
oxidoreductase activity, acting on sulfur group of donors | 6.3477E-3 | 2 | 20 | 1 | 6292 |