Sequence of the PAS8 gene, the product of which is essential for biogenesis of peroxisomes in Saccharomyces cerevisiae

Biochim Biophys Acta. 1993 Nov 16;1216(2):325-8. doi: 10.1016/0167-4781(93)90166-b.

Abstract

In a genetic screen for mutants disturbed in peroxisomal functions we found that the laboratory 'wild type' strain YP102 behaved like a typical peroxisome assembly mutant. Here, we report the sequence of the complementing gene (PAS8), coding for a protein of 1030 amino acids that appears to be a novel member of the AAA-protein family which also includes NSFp and PAS1p.

MeSH terms

  • Amino Acid Sequence
  • Base Sequence
  • DNA, Fungal / chemistry
  • Fungal Proteins / genetics*
  • Fungal Proteins / physiology
  • Genes, Fungal*
  • Membrane Proteins / genetics*
  • Membrane Proteins / physiology
  • Microbodies / physiology
  • Molecular Sequence Data
  • Peroxisome-Targeting Signal 1 Receptor
  • Phenotype
  • Receptors, Cytoplasmic and Nuclear
  • Saccharomyces cerevisiae / genetics*
  • Saccharomyces cerevisiae / ultrastructure

Substances

  • DNA, Fungal
  • Fungal Proteins
  • Membrane Proteins
  • Peroxisome-Targeting Signal 1 Receptor
  • Receptors, Cytoplasmic and Nuclear

Associated data

  • GENBANK/L08443
  • GENBANK/L20789
  • GENBANK/X69069
  • GENBANK/X69070
  • GENBANK/X69071
  • GENBANK/X69072
  • GENBANK/X69073
  • GENBANK/X69074
  • GENBANK/X69075
  • GENBANK/X69076