A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase

P Belhumeur; N Fortin; M W Clark

doi:10.1002/yea.320100311

A gene from Saccharomyces cerevisiae which codes for a protein with significant homology to the bacterial 3-phosphoserine aminotransferase

Yeast. 1994 Mar;10(3):385-9. doi: 10.1002/yea.320100311.

Authors

P Belhumeur¹, N Fortin, M W Clark

Affiliation

¹ Department of Microbiology and Immunology, University of Montreal, Quebec, Canada.

PMID: 8017107
DOI: 10.1002/yea.320100311

Abstract

During the sequencing of the gene GSP2 from Saccharomyces cerevisiae, we have encountered an adjacent open reading frame having strong homology to the 3-phosphoserine aminotransferase (E.C.2.6.1.52) from other organisms. In this report, we present the sequence for this yeast SERC, and evidence that its deletion from the yeast genome leads to serine dependency. The sequence has been deposited in the GenBank data library under Accession Number L20917.

Publication types

Comparative Study
Research Support, Non-U.S. Gov't

MeSH terms

Amino Acid Sequence
Base Sequence
Fungal Proteins / genetics*
GTP-Binding Proteins / genetics
Genes, Fungal / genetics*
Genetic Complementation Test
Molecular Sequence Data
Monomeric GTP-Binding Proteins*
Nuclear Proteins / genetics
Open Reading Frames / genetics*
Saccharomyces cerevisiae / genetics*
Saccharomyces cerevisiae Proteins*
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Serine / metabolism
Transaminases / genetics*

Substances

Fungal Proteins
Nuclear Proteins
Saccharomyces cerevisiae Proteins
Serine
Transaminases
phosphoserine aminotransferase
GTP-Binding Proteins
GSP2 protein, S cerevisiae
Monomeric GTP-Binding Proteins

Associated data

GENBANK/L20917